Ontology highlight
ABSTRACT:
SUBMITTER: Clement C
PROVIDER: S-EPMC2064392 | biostudies-other | 2006 Sep
REPOSITORIES: biostudies-other
The Journal of cell biology 20060901 7
It is becoming increasingly clear that herpesviruses can exploit the endocytic pathway to infect cells, yet several important features of this process remain poorly defined. Using herpes simplex virus-1 (HSV-1) as a model, we demonstrate that endocytosis of the virions mimic many features of phagocytosis. During entry, HSV-1 virions associated with plasma membrane protrusions followed by a phagocytosis-like uptake involving rearrangement of actin cytoskeleton and trafficking of the virions in la ...[more]