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Site-specific insertion of three structural gene cassettes in transposon Tn7.

ABSTRACT: Transposon Tn7 has been known to carry genes for resistance to trimethoprim and spectinomycin. A poorly expressed streptothricin resistance gene, identical to the sat gene found in transposons Tn1825 and Tn1826, was localized between the two mentioned genes in Tn7. The surroundings of all three resistance genes indicated site-specific insertion of genetic cassettes.

SUBMITTER: Sundstrom L

PROVIDER: S-EPMC207888 | biostudies-other | 1991 May

REPOSITORIES: biostudies-other

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Site-specific insertion of three structural gene cassettes in transposon Tn7.

Sundström L L Roy P H PH Sköld O O

Journal of bacteriology 19910501 9

Transposon Tn7 has been known to carry genes for resistance to trimethoprim and spectinomycin. A poorly expressed streptothricin resistance gene, identical to the sat gene found in transposons Tn1825 and Tn1826, was localized between the two mentioned genes in Tn7. The surroundings of all three resistance genes indicated site-specific insertion of genetic cassettes. ...[more]

PMID: 1850404

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