Ontology highlight
ABSTRACT:
SUBMITTER: Bennett MJ
PROVIDER: S-EPMC2143041 | biostudies-other | 1995 Dec
REPOSITORIES: biostudies-other
Protein science : a publication of the Protein Society 19951201 12
3D domain swapping is a mechanism for forming oligomeric proteins from their monomers. In 3D domain swapping, one domain of a monomeric protein is replaced by the same domain from an identical protein chain. The result is an intertwined dimer or higher oligomer, with one domain of each subunit replaced by the identical domain from another subunit. The swapped "domain" can be as large as an entire tertiary globular domain, or as small as an alpha-helix or a strand of a beta-sheet. Examples of 3D ...[more]