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Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase.

ABSTRACT: We purified CALLA from human kidney and isolated a cDNA clone reactive with two oligonucleotide probes corresponding to two distinct peptides. The amino acid sequence translated from the CALLA cDNA revealed 100% identity with that of human neutral endopeptidase (NEP, enkephalinase). The distribution of CALLA antigen and NEP in normal tissues are similar.

SUBMITTER: Letarte M

PROVIDER: S-EPMC2189092 | biostudies-other | 1988 Oct

REPOSITORIES: biostudies-other

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Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase.

Letarte M M Vera S S Tran R R Addis J B JB Onizuka R J RJ Quackenbush E J EJ Jongeneel C V CV McInnes R R RR

The Journal of experimental medicine 19881001 4

We purified CALLA from human kidney and isolated a cDNA clone reactive with two oligonucleotide probes corresponding to two distinct peptides. The amino acid sequence translated from the CALLA cDNA revealed 100% identity with that of human neutral endopeptidase (NEP, enkephalinase). The distribution of CALLA antigen and NEP in normal tissues are similar. ...[more]

PMID: 2971756

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