Ontology highlight
ABSTRACT:
SUBMITTER: Burd PR
PROVIDER: S-EPMC2191950 | biostudies-other | 1995 Apr
REPOSITORIES: biostudies-other
Burd P R PR Thompson W C WC Max E E EE Mills F C FC
The Journal of experimental medicine 19950401 4
When mast cells are activated through their immunoglobulin (Ig)E receptors, release of low molecular weight mediators like histamine is followed by secretion of multiple cytokines, including interleukin (IL)-3, IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor. Here we report that stimulated mast cells also synthesize IL-13 mRNA and protein; secretion of this cytokine may be of particular importance because of its ability to stimulate IgE expression. IL-13 transcripts detected by ...[more]