Ontology highlight
ABSTRACT:
SUBMITTER: Loetscher M
PROVIDER: S-EPMC2192763 | biostudies-other | 1996 Sep
REPOSITORIES: biostudies-other
The Journal of experimental medicine 19960901 3
A human receptor that is selective for the CXC chemokines IP10 and Mig was cloned and characterized. The receptor cDNA has an open reading frame of 1104-bp encoding a protein of 368 amino acids with a molecular mass of 40,659 dalton. The sequence includes seven putative transmembrane segments characteristic of G-protein coupled receptors. It shares 40.9 and 40.3% identical amino acids with the two IL-8 receptors, and 34.2-36.9% identity with the five known CC chemokine receptors. The IP10/Mig re ...[more]