Ontology highlight
ABSTRACT:
SUBMITTER: Aguilera-Romero A
PROVIDER: S-EPMC2265561 | biostudies-other | 2008 Feb
REPOSITORIES: biostudies-other
Aguilera-Romero Auxiliadora A Kaminska Joanna J Spang Anne A Riezman Howard H Muñiz Manuel M
The Journal of cell biology 20080218 4
The p24 family members are transmembrane proteins assembled into heteromeric complexes that continuously cycle between the ER and the Golgi apparatus. These cargo proteins were assumed to play a structural role in COPI budding because of their major presence in mammalian COPI vesicles. However, this putative function has not been proved conclusively so far. Furthermore, deletion of all eight yeast p24 family members does not produce severe transport phenotypes, suggesting that the p24 complex is ...[more]