Ontology highlight
ABSTRACT:
SUBMITTER: Meragelman TL
PROVIDER: S-EPMC2288652 | biostudies-other | 2007 Jul
REPOSITORIES: biostudies-other
Journal of natural products 20070612 7
Fractionation of cytotoxic extracts of specimens of a newly described sponge genus, Candidaspongia, has yielded the candidaspongiolides (3), a complex mixture of acyl esters of a macrolide related to tedanolide. The general structure of the candidaspongiolides was determined by analyses of various 2D NMR and MS data sets. The acyl ester components were identified by GC-MS analysis of the derived fatty acid methyl esters. The mixture could be selectively converted to the deacylated macrolide core ...[more]