A Mycobacterium tuberculosis IS6110 preferential locus (ipl) for insertion into the genome.

ABSTRACT: A 267-nucleotide Mycobacterium tuberculosis genomic sequence (ipl, the IS6110 preferential locus) which can harbor the insertion sequence IS6110 at six alternative locations has been identified in some three-quarters of the isolates tested. Only one IS6110 copy was observed at this locus in the ipl::IS6110(+)-containing isolates tested, and all insertions had the same orientation. The implications of this finding for IS6110 fingerprint typing methods is discussed in this work.

SUBMITTER: Fang Z 

PROVIDER: S-EPMC229605 | biostudies-other | 1997 Feb

REPOSITORIES: biostudies-other