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Determination of genotypes of hepatitis C virus in Venezuela by restriction fragment length polymorphism.


ABSTRACT: Hepatitis C virus genotypes in Venezuela were analyzed by restriction fragment length polymorphism in the 5' noncoding region. The absence of BstUI digestion was found to be a useful marker for genotype 2 specimens. From 122 serum samples, 66, 20, and 2.5% were classified as genotypes 1, 2, and 3, respectively; 0.8% were classified as genotype 4; and 10% appeared to be mixed infections.

SUBMITTER: Pujol FH 

PROVIDER: S-EPMC229860 | biostudies-other | 1997 Jul

REPOSITORIES: biostudies-other

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Determination of genotypes of hepatitis C virus in Venezuela by restriction fragment length polymorphism.

Pujol F H FH   Loureiro C L CL   Devesa M M   Blitz L L   Parra K K   Beker S S   Liprandi F F  

Journal of clinical microbiology 19970701 7


Hepatitis C virus genotypes in Venezuela were analyzed by restriction fragment length polymorphism in the 5' noncoding region. The absence of BstUI digestion was found to be a useful marker for genotype 2 specimens. From 122 serum samples, 66, 20, and 2.5% were classified as genotypes 1, 2, and 3, respectively; 0.8% were classified as genotype 4; and 10% appeared to be mixed infections. ...[more]

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