Ontology highlight
ABSTRACT:
SUBMITTER: Desrosiers RC
PROVIDER: S-EPMC230286 | biostudies-other | 1997 Dec
REPOSITORIES: biostudies-other
Desrosiers R C RC Sasseville V G VG Czajak S C SC Zhang X X Mansfield K G KG Kaur A A Johnson R P RP Lackner A A AA Jung J U JU
Journal of virology 19971201 12
A herpesvirus that is related to but distinct from the Kaposi's sarcoma-associated herpesvirus (KSHV, or human herpesvirus 8) was isolated from rhesus monkeys. The sequence of 10.6 kbp from virion DNA revealed the presence of an interleukin-6 homolog similar to what is present in KSHV and a closer relatedness of the DNA polymerase and glycoprotein B reading frames to those of KSHV than to those of any other herpesvirus. This rhesus monkey herpesvirus replicated lytically and to high titers in cu ...[more]