Ontology highlight
ABSTRACT:
SUBMITTER: Lewis TL
PROVIDER: S-EPMC236266 | biostudies-other | 1994 Jan
REPOSITORIES: biostudies-other
Journal of virology 19940101 1
We report the results from sequence analysis and expression studies of the gastroenteritis agent astrovirus serotype 1. We have cloned and sequenced 5,944 nucleotides (nt) of the estimated 7.2-kb RNA genome and have identified three open reading frames (ORFs). ORF-3, at the 3' end, is 2,361 nt in length and is fully encoded in both the genomic and subgenomic viral RNAs. Expression of ORF-3 in vitro yields an 87-kDa protein that is immunoprecipitated with a monoclonal antibody specific for viral ...[more]