Ontology highlight
ABSTRACT:
SUBMITTER: Martell M
PROVIDER: S-EPMC236838 | biostudies-other | 1994 May
REPOSITORIES: biostudies-other
Martell M M Esteban J I JI Quer J J Vargas V V Esteban R R Guardia J J Gómez J J
Journal of virology 19940501 5
We have studied the distribution of viral sequences from the 5' noncoding region and from a fragment of the E2/NS2 region of the hepatitis C virus (HCV) genome in samples obtained before and after liver transplantation in two patients with HCV cirrhosis. The population of viral sequences in both regions were established by sequencing cloned PCR products. In both cases, the complexity of the viral quasispecies decreased after transplantation, although the consensus nucleotide and amino acid seque ...[more]