Experimental vaccine protection against homologous and heterologous strains of feline immunodeficiency virus.
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ABSTRACT:
SUBMITTER: Yamamoto JK
PROVIDER: S-EPMC237403 | biostudies-other | 1993 Jan
REPOSITORIES: biostudies-other
Publications
Experimental vaccine protection against homologous and heterologous strains of feline immunodeficiency virus.
Yamamoto J K JK Hohdatsu T T Olmsted R A RA Pu R R Louie H H Zochlinski H A HA Acevedo V V Johnson H M HM Soulds G A GA Gardner M B MB
Journal of virology 19930101 1
More than 90% of cats immunized with inactivated whole infected-cell or cell-free feline immunodeficiency virus (FIV) vaccines were protected against intraperitoneal infection with 10 50% animal infectious doses of either homologous FIV Petaluma (28 of 30 cats) or heterologous FIV Dixon strain (27 of 28 cats). All 15 control cats were readily infected with either strain of FIV. Protection appears to correlate with antiviral envelope antibody levels by a mechanism yet to be determined. ...[more]
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