Ontology highlight
ABSTRACT:
SUBMITTER: Guiserix M
PROVIDER: S-EPMC2396208 | biostudies-other | 2007 Dec
REPOSITORIES: biostudies-other
Journal of the Royal Society, Interface 20071201 17
In the year 1994, the Serengeti lion population was decimated by a canine distemper disease outbreak. Retrospective investigations showed that this host population had already been in contact with the pathogen in 1981 without any detected sign of disease. As an alternative to the virus mutation hypothesis to explain this difference in virulences observed in 1981 and 1994, we propose a novel mechanism of disease emergence based on variation in population immunity. We use a stochastic model to sho ...[more]