Ontology highlight
ABSTRACT:
SUBMITTER: Lee JH
PROVIDER: S-EPMC2440477 | biostudies-other | 2008 Jul
REPOSITORIES: biostudies-other
Lee Jung-Ho JH Bhak Ghibom G Lee Sang-Gil SG Paik Seung R SR
Biophysical journal 20080509 2
Amyloid fibrils found in various neurodegenerative disorders are also recognized as high-performance protein nanomaterials with a formidable rigidity. Elucidation of an underlying molecular mechanism of the amyloid fibril formation is crucial not only to develop controlling strategy toward the diseases, but also to apply the protein fibrils for future nanobiotechnology. alpha-Synuclein is an amyloidogenic protein responsible for the radiating filament formation within Lewy bodies of Parkinson's ...[more]