The nucleotide sequence, 5' end, promoter domain, and kinetics of expression of the gene encoding the herpes simplex virus type 2 latency-associated transcript.
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ABSTRACT:
SUBMITTER: Krause PR
PROVIDER: S-EPMC249080 | biostudies-other | 1991 Oct
REPOSITORIES: biostudies-other
Publications
The nucleotide sequence, 5' end, promoter domain, and kinetics of expression of the gene encoding the herpes simplex virus type 2 latency-associated transcript.
Krause P R PR Ostrove J M JM Straus S E SE
Journal of virology 19911001 10
The sequence of the herpes simplex virus type 2 (HSV-2) latency-associated transcript (LAT) region resembles that of HSV-1 only where the LATs overlap ICP0 and in the putative promoter region. Otherwise, the LAT 5' ends, kinetics of expression, and promoter elements are mostly conserved between HSV-1 and HSV-2. The remaining differences between the LATs could contribute to each virus's distinctive pattern of reactivation. ...[more]
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