Ontology highlight
ABSTRACT:
SUBMITTER: Chen MW
PROVIDER: S-EPMC2533225 | biostudies-other | 2008 Sep
REPOSITORIES: biostudies-other
Chen Ming-Wei MW Cheng Ting-Jen Rachel TJ Huang Yaoxing Y Jan Jia-Tsrong JT Ma Shiou-Hwa SH Yu Alice L AL Wong Chi-Huey CH Ho David D DD
Proceedings of the National Academy of Sciences of the United States of America 20080902 36
H5N1 influenza viruses have spread extensively among wild birds and domestic poultry. Cross-species transmission of these viruses to humans has been documented in over 380 cases, with a mortality rate of approximately 60%. There is great concern that a H5N1 virus would acquire the ability to spread efficiently between humans, thereby becoming a pandemic threat. An H5N1 influenza vaccine must, therefore, be an integral part of any pandemic preparedness plan. However, traditional methods of making ...[more]