Ontology highlight
ABSTRACT:
SUBMITTER: Raijmakers R
PROVIDER: S-EPMC2556017 | biostudies-other | 2008 Sep
REPOSITORIES: biostudies-other
Raijmakers Reinout R Berkers Celia R CR de Jong Annemieke A Ovaa Huib H Heck Albert J R AJ Mohammed Shabaz S
Molecular & cellular proteomics : MCP 20080604 9
Quantitation of protein abundance is a vital component in the proteomic analysis of biological systems, which can be achieved by differential stable isotopic labeling. To analyze tissue-derived samples, the isotopic labeling can be performed using chemical labeling of the peptides post-digestion. Standard chemical labeling procedures often require many manual sample handling steps, reducing the accuracy of measurements. Here, we describe a fully automated, online (in nanoLC columns), labeling pr ...[more]