Polyethylene wear is influenced by manufacturing technique in modular TKA.
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ABSTRACT:
SUBMITTER: Lombardi AV
PROVIDER: S-EPMC2565045 | biostudies-other | 2008 Nov
REPOSITORIES: biostudies-other
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Project description:UNLABELLED: Restoration of femoral offset and acetabular inclination may have an effect on polyethylene (PE) wear in THA. We therefore assessed the effect of femoral offset and acetabular inclination (angle) on acetabular conventional (not highly cross-linked) PE wear in uncemented THA. We prospectively followed 43 uncemented THAs for a minimum of 49 months (mean, 64 months; range, 49-88 months). Radiographs were assessed for femoral offset, acetabular inclination, and conventional PE wear. The mean (+/- standard deviation) linear wear rate in all THAs was 0.14 mm/year (+/- 0.01 mm/year) and the mean volumetric wear rate was 53.1 mm(3)/year (+/- 5.5 mm(3)/year). In THAs with an acetabular angle less than 45 degrees , the mean wear was 0.12 mm/year (+/- 0.01 mm/year) compared with 0.18 mm/year (+/- 0.02 mm/year) in those with a reconstructed acetabular angle greater than 45 degrees . Reproduction of a reconstructed femoral offset to within 5 mm of the native femoral offset was associated with a reduction in conventional PE wear (0.12 mm/year versus 0.16 mm/year). Careful placement of the acetabular component to ensure an acetabular angle less than 45 degrees in the reconstructed hip allows for reduced conventional PE wear. LEVEL OF EVIDENCE: Level II, prospective study. See Guidelines for Authors for a complete description of levels of evidence.
| S-EPMC2758973 | biostudies-other
Project description:UNLABELLED: Oxidized zirconium, a material with a ceramic surface on a metal substrate, and highly cross-linked polyethylene are two materials developed to reduce wear. We measured in vivo femoral head penetration in patients with these advanced bearings. We hypothesized the linear wear rates would be lower than those published for cobalt-chrome and standard polyethylene. We retrospectively reviewed a select series of 56 THAs in a relatively young, active patient population utilizing oxidized zirconium femoral heads and highly cross-linked polyethylene acetabular liners. Femoral head penetration was determined using the Martell computerized edge-detection method. All patients were available for 2-year clinical and radiographic followup. True linear wear was 4 microm/year (95% confidence intervals, +/- 59 microm/year). The early wear rates in this cohort of relatively young, active patients were low and we believe justify the continued study of these alternative bearing surfaces. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
| S-EPMC2600989 | biostudies-other
Project description:Background and purpose - Backside wear of the polyethylene insert in total knee arthroplasty (TKA) can produce clinically significant levels of polyethylene debris, which can lead to loosening of the tibial component. Loosening due to polyethylene debris could theoretically be reduced in tibial components of monoblock polyethylene design, as there is no backside wear. We investigated the effect of 2 different tibial component designs, monoblock and modular polyethylene, on migration of the tibial component in uncemented TKA. Patients and methods - In this randomized study, 53 patients (mean age 61 years), 32 in the monoblock group and 33 in the modular group, were followed for 2 years. Radiostereometric analysis (RSA) was done postoperatively after weight bearing and after 3, 6, 12, and 24 months. The primary endpoint of the study was comparison of the tibial component migration (expressed as maximum total point motion (MTPM)) of the 2 different implant designs. Results - We did not find any statistically significant difference in MTPM between the groups at 3 months (p = 0.2) or at 6 months (p = 0.1), but at 12 and 24 months of follow-up there was a significant difference in MTPM of 0.36?mm (p = 0.02) and 0.42?mm (p = 0.02) between groups, with the highest amount of migration (1.0?mm) in the modular group. The difference in continuous migration (MTPM from 12 and 24 months) between the groups was 0.096?mm (p = 0.5), and when comparing MTPM from 3-24 months, the difference between the groups was 0.23?mm (p = 0.07). Interpretation - In both study groups, we found the early migration pattern expected, with a relatively high initial amount of migration from operation to 3 months of follow-up, followed by stabilization of the implant with little migration thereafter. However, the modular implants had a statistically significantly higher degree of migration compared to the monoblock. We believe that the greater stiffness of the modular implants was the main reason for the difference in migration, but an initial creep in the polyethylene metal-back locking mechanism of the modular group could also be a possible explanation for the observed difference in migration between the 2 study groups.
| S-EPMC5119444 | biostudies-literature
Project description:BackgroundCross-linked polyethylene (XLPE) liners have shown lower wear rates than conventional polyethylene liners in total hip arthroplasty. The primary aim of our study was to report our most recent analysis of wear rates and clinical outcomes of a third-generation XLPE liner. Secondary aims were to investigate the rate of adverse events related to mechanical failure or oxidation of this liner.MethodsA series of 266 total hip arthroplasties using a specific XLPE liner were retrospectively reviewed. Radiographs were examined to determine linear and volumetric wear rates and presence of osteolysis. Clinical outcomes, revision rates, mechanical failures, and risk factors for accelerated polyethylene wear were additionally investigated.ResultsThe mean age at the time of surgery was 65.8 years and the mean follow-up was 5.5 years. The mean linear wear rate was 0.003 mm/year and the mean volumetric wear rate was 0.42 mm3/year, and there was no evidence of osteolysis. Harris hip scores increased from 50.9 preoperatively to 96.0 at the latest follow-up. The revision rate was 0.4%, with no liner rim fractures and no liner dissociations/loosenings. Femoral head material, head size, age, body mass index, and time since implantation had no effect on wear rates.ConclusionWear rates for this third-generation XLPE liner were low at mid-term follow-up, and no adverse sequelae of oxidation or deleterious mechanical properties were observed. This remained true regardless of femoral head size and material or patient age and body mass index. Further analysis will be necessary to ensure continued wear resistance, oxidative stability, and mechanical strength at long-term follow-up.
| S-EPMC7267711 | biostudies-literature
Project description:BackgroundHighly crosslinked polyethylene (HXLPE) was introduced to reduce wear and osteolysis in total joint arthroplasty. While many studies report wear and osteolysis associated with HXLPE, analytical techniques, clinical study design and followup, HXLPE formulation and implant design characteristics, and patient populations differ substantially among investigations, complicating a unified perspective.Questions/purposesLiterature on first-generation HXLPE was summarized. We systematically reviewed the radiographic wear data and incidence of osteolysis for HXLPE in hip and knee arthroplasty.MethodsPubMed identified 391 studies; 28 met inclusion criteria for a weighted-averages analysis of two-dimensional femoral head penetration rates. To determine the incidence of osteolysis, we estimated a pooled odds ratio using a random-effects model.ResultsWeighted-averages analyses of femoral head penetration rates in HXLPE liners and conventional UHMWPE liners resulted, respectively, in a mean two-dimensional linear penetration rate of 0.042 mm/year based on 28 studies (n=1503 hips) and 0.137 mm/year based on 18 studies (n=695 hips). The pooled odds ratio for the risk of osteolysis in HXLPE versus conventional liners was 0.13 (95% confidence interval, 0.06-0.27) among studies with minimum 5-year followup. We identified two clinical studies of HXLPE in TKA, preventing systematic analysis of outcomes.ConclusionsHXLPE liner studies consistently report lower femoral head penetration and an 87% lower risk of osteolysis. Reduction in femoral head penetration or osteolysis risk is not established for large-diameter (>32 mm) metallic femoral heads or ceramic femoral heads of any size. Few studies document the clinical performance of HXLPE in knees.
| S-EPMC3126942 | biostudies-literature
Project description:BackgroundWear, oxidation, and particularly rim impingement damage of ultra-high molecular weight polyethylene total disc replacement components have been observed following surgical revision. However, neither in vitro testing nor retrieval-based evidence has shown the effect(s) of impingement on the characteristics of polyethylene wear debris. Thus, we sought to determine (1) differences in polyethylene particle size, shape, number, or biological activity that correspond to mild or severe rim impingement and (2) in an analysis of all total disc replacements, regardless of impingement classification, whether there are correlations between the extent of regional damage and the characteristics of polyethylene wear debris.MethodsThe extent of dome and rim damage was characterized for eleven retrieved polyethylene cores obtained at revision surgery after an average duration of implantation of 9.7 years (range, 4.6 to 16.1 years). Polyethylene wear debris was isolated from periprosthetic tissues with use of nitric acid and was imaged with use of environmental scanning electron microscopy. Subsequently, particle size, shape, number, biological activity, and chronic inflammation scores were determined.ResultsGrouping of particles by size ranges that represented high biological relevance (<0.1 to 1-μm particles), intermediate biological relevance (1 to 10-μm particles), and low biological relevance (>10-μm particles) revealed an increased volume fraction of particles in the <0.1 to 1-μm and 1 to 10-μm size ranges in the mild-impingement cohort as compared with the severe-impingement cohort. The increased volume fractions resulted in a higher specific biological activity per unit particle volume in the mild-impingement cohort than in the severe-impingement cohort. However, functional biological activity, which is normalized by particle volume (mm3/g of tissue), was significantly higher in the severe-impingement cohort. This increase was due to a larger volume of particles in all three size ranges. In both cohorts, the functional biological activity correlated with the chronic inflammatory response, and the extent of rim penetration positively correlated with increasing particle size, number, and functional biological activity.ConclusionsThe results of this study suggest that severe rim impingement increases the production of biologically relevant particles from motion-preserving lumbar total disc replacement components.Level of evidencePrognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
| S-EPMC3748985 | biostudies-literature
Project description:Powder bed additive manufacturing (AM) processes, including binder jetting (BJAM) and powder bed fusion (PBF), can manufacture complex three-dimensional components from a variety of materials. A fundamental understanding of the spreading of thin powder layers is essential to develop robust process parameters for powder bed AM and to assess the influence of powder feedstock characteristics on the subsequent process outcomes. Toward meeting these needs, this work presents the design, fabrication, and qualification of a testbed for modular, mechanized, multi-layer powder spreading. The testbed is designed to replicate the operating conditions of commercial AM equipment, yet features full control over motion parameters including the translation and rotation of a roller spreading tool and precision motion of a feed piston and the build platform. The powder spreading mechanism is interchangeable and therefore can be customized, including the capability for dispensing of fine, cohesive powders using a vibrating hopper. Validation of the resolution and accuracy of the machine and its subsystems, as well as the spreading of exemplary layers from a range of powder sizes typical of BJAM and PBF processes, are described. The precision engineered testbed can therefore enable the optimization of powder spreading parameters for AM and correlation to build process parameters in future work, as well as exploration of spreading of specialized powders for AM and other techniques.
| S-EPMC7880620 | biostudies-literature
Project description:Road dust cotains tire wear particles (TWPs) and a large amount of mineral particles (MPs). Given that tire tread in vehicles is mainly comprised of natural rubber (NR), isoprene and dipentene could be the main pyrogenic products stemmed from the thermolysis of NR. This offers a great chance to quantify the exact mass of TWP in road dust. As such, this study focused on the influence of MPs on the trends in thermolytic behaviors of NR using the resistive furnace (furnance) and Curie point pyrolyzers. This study confirmed that a reliable correlation in line with the formation of isoprene and dipentene could not be realized using the furnace type of a pyrolyzer. This means that employing the furnace type of a pyrolyzer in quantitification of TWPs could not be a viable and approproiate option due to the diverted thermolytic trends of NR due to differences in the heat transfer and adsoprtion of the pyrogenic products triggered by MPs. In the Curie point type of a pyrolyzer, the production rates of isoprene and dipentene were linearly responded to the mass of NR. The ferromagnetic substance in MPs could lead to the thermolytic trend change of NR. Thus, adopting the Curie point type of a pyrolyzer could be a viable option for quantification of TWPs in road dust when the effects of ferromagnetic substance are well neutralized.
| S-EPMC10359866 | biostudies-literature
Project description:BackgroundWhen using the gap-balancing technique for TKA, excessive medial release and varus proximal tibial resection can be associated with internal rotation of the femoral component. Previous studies have evaluated the causes of femoral component rotational alignment with a separate factor analysis using unadjusted statistical methods, which might result in treatment effects being attributed to confounding variables.Questions/purposes(1) What pre- and intraoperative factors are associated with internal rotation of the femoral component in TKA using the gap balancing technique? (2) To what degree does femoral component rotation as defined by the navigation system differ from rotation as measured by postoperative CT?MethodsThree hundred seventy-seven knees that underwent computer-assisted primary TKA attributable to degenerative osteoarthritis with varus or mild valgus alignment in which medial soft tissue release was performed, and those with preoperative radiographs including preoperative CT between October 2007 and June 2014 were included in the study. To achieve a balanced mediolateral gap, the structures released during each medial release step were as follows: Step 1, deep medial collateral ligament (MCL); Step 2, superficial MCL (proximal, above the pes anserine tendon) and semimembranosus tendon; and Step 3, the superficial MCL (distal, below the pes anserine tendon). Knees with internal rotation of the femoral component, which was directed by navigation, to achieve a rectangular mediolateral flexion gap were considered cases, and knees without internally rotated femoral components were considered controls. Univariable analysis of the variables (age, sex, BMI, operated side, preoperative hip-knee-ankle angle, preoperative medial proximal tibial angle, preoperative rotation degree of the clinical transepicondylar axis [TEA] relative to the posterior condylar axis [PCA], coronal angle of resected tibia, resection of the posterior cruciate ligament, type of prosthesis, and extent of medial release) of cases and controls was performed, followed by a multivariable logistic regression analysis on those factors where p equals 0.15 or less. For an evaluation of navigation error, 88 knees that underwent postoperative CT were analyzed. Postoperative CT scans were obtained for patients with unexplained pain or stiffness after the operations. Using the paired t-test and Pearson's correlation analysis, the postoperative TEA-PCA measured with postoperative CT was compared with theoretical TEA-PCA, which was calculated with preoperative TEA-PCA and actual femoral component rotation checked by the navigation system.ResultsAfter controlling for a relevant confounding variable such as postoperative hip-knee-ankle angle, we found that the extent of medial release (Step 1 as reference; Step 2: odds ratio [OR], 5.7, [95% CI, 2.2-15]; Step 3: OR, 22, [95% CI, 7.8-62], p < 0.001) was the only factor we identified that was associated with internal rotation of the femoral component. With the numbers available, we found no difference between the mean theoretical postoperative TEA-PCA and the postoperative TEA-PCA measured using postoperative CT (4.8° ± 2.7º versus 5.0° ± 2.3º; mean difference, 0.2° ± 1.5º; p = 0.160).ConclusionsExtent of medial release was the only factor we identified that was associated with internal rotation of the femoral component in gap-balancing TKA. To avoid internal rotation of the femoral component, we recommend a carefully subdivided medial-releasing technique, especially for the superficial MCL because once the superficial MCL has been completely released it cannot easily be restored.Level of evidenceLevel III, therapeutic study.
| S-EPMC5498379 | biostudies-literature
Project description:Some previous studies suggest that aging influences wear and oxidatively degraded nonsterilized ultra-high-molecular-weight polyethylene (UHMWPE) exhibits decreased wear resistance. We therefore asked whether shelf-aging storage conditions influenced degradation and wear resistance of gamma-irradiated UHMWPE. We examined oxidation and wear of 100-Mrad gamma-irradiated UHMWPE (100-Mrad polyethylene) cups shelf-aged for 30 years without (n=2) or with (n=2) packages. The oxidation index of the unpackaged 100-Mrad polyethylene surface (4) was higher than that of the packaged one (2.7). The packaged 100-Mrad polyethylene cup exhibited a high wear resistance with a steady wear rate of 0.5 mg/10(6) cycles. In contrast, the unpackaged 100-Mrad polyethylene exhibited an extremely high initial wear rate of 187.9 mg/10(6) cycles over the first 0.25 x 10(6) cycles with a subsequently reduced wear rate of 5 mg/10(6) cycles after 5 x 10(6) cycles. Packaging over long periods inhibits surface oxidation and maintains the wear resistance of gamma-irradiated UHMWPE cups.
| S-EPMC2505127 | biostudies-other