Ontology highlight
ABSTRACT:
SUBMITTER: Miyamoto M
PROVIDER: S-EPMC257947 | biostudies-other | 1991 Jun
REPOSITORIES: biostudies-other
Miyamoto M M Noji S S Kokeguchi S S Kato K K Kurihara H H Murayama Y Y Taniguchi S S
Infection and immunity 19910601 6
We isolated and characterized an immunogenic protein of an oral spirochete, Treponema denticola Johnson. A genomic DNA library constructed with bacteriophage lambda EMBL3 as a vector was immunologically screened with a rabbit antiserum against the whole cells. Using Western immunoblot analysis, we found a particular clone encoding an antigen with a molecular weight of 53,000; we designated the antigen as T. denticola protein A (TdpA). Complete sequence determination revealed an open reading fram ...[more]