Ontology highlight
ABSTRACT:
SUBMITTER: Wightman R
PROVIDER: S-EPMC2593189 | biostudies-other | 2008 Dec
REPOSITORIES: biostudies-other
Wightman Raymond R Bell Rachel R Reece Richard J RJ
Eukaryotic cell 20081024 12
In Saccharomyces cerevisiae, the GAL genes encode the enzymes required for galactose metabolism. Regulation of these genes has served as the paradigm for eukaryotic transcriptional control over the last 50 years. The switch between inert and active gene expression is dependent upon three proteins--the transcriptional activator Gal4p, the inhibitor Gal80p, and the ligand sensor Gal3p. Here, we present a detailed spatial analysis of the three GAL regulatory proteins produced from their native geno ...[more]