Ontology highlight
ABSTRACT:
SUBMITTER: Deng Y
PROVIDER: S-EPMC2613206 | biostudies-other | 2009 Jan
REPOSITORIES: biostudies-other
Deng Yi Y Golinelli-Cohen Marie-Pierre MP Smirnova Elena E Jackson Catherine L CL
EMBO reports 20081128 1
Arf (ADP-ribosylation factor) family small G proteins are crucial regulators of intracellular transport. The active GTP-bound form of Arf interacts with a set of proteins--effectors--which mediate the downstream signalling events of Arf activation. A well-studied class of Arf1 effectors comprises the coat complexes, such as the cis-Golgi-localized COPI (coat protein complex I) coat, and trans-Golgi network-endosomal clathrin coats. At least five different coats require Arf1-GTP to localize to or ...[more]