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West Nile encephalitis in Israel, 1999: the New York connection.

ABSTRACT: We describe two cases of West Nile (WN) encephalitis in a married couple in Tel Aviv, Israel, in 1999. Reverse transcription-polymerase chain reaction performed on a brain specimen from the husband detected a WN viral strain nearly identical to avian strains recovered in Israel in 1998 (99.9% genomic sequence homology) and in New York in 1999 (99.8%). This result supports the hypothesis that the 1999 WN virus epidemic in the United States originated from the introduction of a strain that had been circulating in Israel.

SUBMITTER: Giladi M

PROVIDER: S-EPMC2631756 | biostudies-other | 2001 Jul-Aug

REPOSITORIES: biostudies-other

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West Nile encephalitis in Israel, 1999: the New York connection.

Giladi M M Metzkor-Cotter E E Martin D A DA Siegman-Igra Y Y Korczyn A D AD Rosso R R Berger S A SA Campbell G L GL Lanciotti R S RS

Emerging infectious diseases 20010701 4

We describe two cases of West Nile (WN) encephalitis in a married couple in Tel Aviv, Israel, in 1999. Reverse transcription-polymerase chain reaction performed on a brain specimen from the husband detected a WN viral strain nearly identical to avian strains recovered in Israel in 1998 (99.9% genomic sequence homology) and in New York in 1999 (99.8%). This result supports the hypothesis that the 1999 WN virus epidemic in the United States originated from the introduction of a strain that had bee ...[more]

PMID: 11585528

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