Ontology highlight
ABSTRACT:
SUBMITTER: Zhu TF
PROVIDER: S-EPMC2661144 | biostudies-other | 2009
REPOSITORIES: biostudies-other
Preparation of monodisperse vesicles is important both for research purposes and for practical applications. While the extrusion of vesicles through small pores (approximately 100 nm in diameter) results in relatively uniform populations of vesicles, extrusion to larger sizes results in very heterogeneous populations of vesicles. Here we report a simple method for preparing large monodisperse multilamellar vesicles through a combination of extrusion and large-pore dialysis. For example, extrusio ...[more]