Ontology highlight
ABSTRACT:
SUBMITTER: Cuddihy AR
PROVIDER: S-EPMC2661859 | biostudies-other | 2009 Mar
REPOSITORIES: biostudies-other
Cuddihy Andrew R AR Ge Shundi S Zhu Judy J Jang Julie J Chidgey Ann A Thurston Gavin G Boyd Richard R Crooks Gay M GM
Blood 20081216 12
Although the mechanisms of cross-talk that regulate the hematopoietic and epithelial compartments of the thymus are well established, the interactions of these compartments with the thymic endothelium have been largely ignored. Current understanding of the thymic vasculature is based on studies of adult thymus. We show that the neonatal period represents a unique phase of thymic growth and differentiation, marked by endothelium that is organized as primitive, dense networks of capillaries depend ...[more]