From cancer genomes to cancer models: bridging the gaps.
Ontology highlight
ABSTRACT:
SUBMITTER: Baudot A
PROVIDER: S-EPMC2672900 | biostudies-other | 2009 Apr
REPOSITORIES: biostudies-other
Publications
From cancer genomes to cancer models: bridging the gaps.
Baudot Anaïs A Real Francisco X FX Izarzugaza José M G JM Valencia Alfonso A
EMBO reports 20090320 4
Cancer genome projects are now being expanded in an attempt to provide complete landscapes of the mutations that exist in tumours. Although the importance of cataloguing genome variations is well recognized, there are obvious difficulties in bridging the gaps between high-throughput resequencing information and the molecular mechanisms of cancer evolution. Here, we describe the current status of the high-throughput genomic technologies, and the current limitations of the associated computational ...[more]
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