The conserved sporulation protein YneE inhibits DNA replication in Bacillus subtilis.
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ABSTRACT:
SUBMITTER: Rahn-Lee L
PROVIDER: S-EPMC2681902 | biostudies-other | 2009 Jun
REPOSITORIES: biostudies-other
Publications
The conserved sporulation protein YneE inhibits DNA replication in Bacillus subtilis.
Rahn-Lee Lilah L Gorbatyuk Boris B Skovgaard Ole O Losick Richard R
Journal of bacteriology 20090327 11
Cells of Bacillus subtilis triggered to sporulate under conditions of rapid growth undergo a marked decrease in chromosome copy number, which was partially relieved by a mutation in the sporulation-induced gene yneE. Cells engineered to express yneE during growth were impaired in viability and produced anucleate cells. We conclude that YneE is an inhibitor of DNA replication. ...[more]
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