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NNAT and DIRAS3 genes are paternally expressed in pigs.


ABSTRACT: Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species. In this study, the polymorphism-based approach was used to detect the imprinting status of NNAT and DIRAS3 genes in five heterozygous pigs (based on SNP) of Large White and Meishan F(1) hybrids. The results show that both genes were paternally expressed in all the tested tissues (heart, liver, spleen, lung, kidney, stomach, small intestine, skeletal muscle, fat, uterus, ovary and pituitary). In addition, the NNAT gene had two transcripts in all tested tissues, which is consistent with its counterpart in man and cattle.

SUBMITTER: Cheng HC 

PROVIDER: S-EPMC2682808 | biostudies-other | 2007 Sep-Oct

REPOSITORIES: biostudies-other

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NNAT and DIRAS3 genes are paternally expressed in pigs.

Cheng Huan-Chen HC   Zhang Feng-Wei FW   Deng Chang-Yan CY   Jiang Cao-De CD   Xiong Yuan-Zhu YZ   Li Feng-E FE   Lei Ming-Gang MG  

Genetics, selection, evolution : GSE 20070927 5


Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species. In this study, the polymorphism-based approach was used to detect the imprinting status of NNAT and DIRAS3 genes in five heterozygous pigs (based on SNP) of Large White and Meishan F(1) hybrids. The results show that both genes were paternally expressed in all the tested tissues (heart, liver, spleen, lung, kidney, stomach, small intest  ...[more]

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2018-10-31 | GSE121980 | GEO