Ontology highlight
ABSTRACT:
SUBMITTER: Mohamed MR
PROVIDER: S-EPMC2683884 | biostudies-other | 2009 Jun
REPOSITORIES: biostudies-other
Mohamed Mohamed R MR Rahman Masmudur M MM Lanchbury Jerry S JS Shattuck Donna D Neff Chris C Dufford Max M van Buuren Nick N Fagan Katharine K Barry Michele M Smith Scott S Damon Inger I McFadden Grant G
Proceedings of the National Academy of Sciences of the United States of America 20090518 22
Identification of the binary interactions between viral and host proteins has become a valuable tool for investigating viral tropism and pathogenesis. Here, we present the first systematic protein interaction screening of the unique variola virus proteome by using yeast 2-hybrid screening against a variety of human cDNA libraries. Several protein-protein interactions were identified, including an interaction between variola G1R, an ankryin/F-box containing protein, and human nuclear factor kappa ...[more]