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Identification of the latex test-reactive protein of Clostridium difficile as glutamate dehydrogenase.


ABSTRACT: Computer analysis showed that the gene encoding the latex test-reactive protein of Clostridium difficile exhibited high levels of homology with glutamate dehydrogenases from various sources. Further analysis demonstrated that the recombinant protein possessed glutamate dehydrogenase activity. Our results show that the protein that reacts in commercial latex tests for C. difficile is a glutamate dehydrogenase.

SUBMITTER: Lyerly DM 

PROVIDER: S-EPMC270394 | biostudies-other | 1991 Nov

REPOSITORIES: biostudies-other

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Identification of the latex test-reactive protein of Clostridium difficile as glutamate dehydrogenase.

Lyerly D M DM   Barroso L A LA   Wilkins T D TD  

Journal of clinical microbiology 19911101 11


Computer analysis showed that the gene encoding the latex test-reactive protein of Clostridium difficile exhibited high levels of homology with glutamate dehydrogenases from various sources. Further analysis demonstrated that the recombinant protein possessed glutamate dehydrogenase activity. Our results show that the protein that reacts in commercial latex tests for C. difficile is a glutamate dehydrogenase. ...[more]

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2015-05-29 | GSE63880 | GEO