Ontology highlight
ABSTRACT:
SUBMITTER: Condac E
PROVIDER: S-EPMC2704898 | biostudies-other | 2009 Aug
REPOSITORIES: biostudies-other
Condac Eduard E Dale George L GL Bender-Neal Diane D Ferencz Beatrix B Towner Rheal R Hinsdale Myron E ME
Glycobiology 20090423 8
Circulating glycosyltransferases including xylosyltransferases I (XylT1) and II (XylT2) are potential serum biomarkers for various diseases. Understanding what influences the serum activity of these enzymes as well as the sources of these enzymes is important to interpreting the significance of alterations in enzyme activity during disease. This article demonstrates that in the mouse and human the predominant XylT in serum is XylT2. Furthermore, that total XylT levels in human serum are approxim ...[more]