Thermodynamics and dynamics of the formation of spherical lipid vesicles.
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ABSTRACT: We propose a free energy expression accounting for the formation of spherical vesicles from planar lipid membranes and derive a Fokker-Planck equation for the probability distribution describing the dynamics of vesicle formation. We find that formation may occur as an activated process for small membranes and as a transport process for sufficiently large membranes. We give explicit expressions for the transition rates and the characteristic time of vesicle formation in terms of the relevant physical parameters.
SUBMITTER: Hernandez-Zapata E
PROVIDER: S-EPMC2710464 | biostudies-other | 2009 Aug
REPOSITORIES: biostudies-other
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