Safety and efficacy of neonatal vaccination.
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ABSTRACT:
SUBMITTER: Demirjian A
PROVIDER: S-EPMC2739303 | biostudies-other | 2009 Jan
REPOSITORIES: biostudies-other
Publications
Safety and efficacy of neonatal vaccination.
Demirjian Alicia A Levy Ofer O
European journal of immunology 20090101 1
Newborns have an immature immune system that renders them at high risk for infection while simultaneously reducing responses to most vaccines, thereby posing challenges in protecting this vulnerable population. Nevertheless, certain vaccines, such as BCG and Hepatitis B vaccine, do demonstrate safety and some efficacy at birth, providing proof of principal that certain antigen-adjuvant combinations are able to elicit protective neonatal responses. Moreover, birth is a major point of healthcare c ...[more]
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