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Organometallic ruthenium complexes with thiosemicarbazone ligands: Synthesis, structure and cytotoxicity of [(eta-p-cymene)Ru(NS)Cl] (NS = 9-anthraldehyde thiosemicarbazones).

ABSTRACT: A series of half-sandwich arene-ruthenium complexes of the type [(eta(6)-p-cymene) Ru(thiosemicarbazone)Cl](+) have been synthesized and their biological activity investigated. The first structurally characterized arene-ruthenium half-sandwich complex with a thiosemicarbazone ligand is reported.

SUBMITTER: Beckford FA

PROVIDER: S-EPMC2769075 | biostudies-other | 2009 Nov

REPOSITORIES: biostudies-other

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Organometallic ruthenium complexes with thiosemicarbazone ligands: Synthesis, structure and cytotoxicity of [(eta-p-cymene)Ru(NS)Cl] (NS = 9-anthraldehyde thiosemicarbazones).

Beckford Floyd A FA Leblanc Gabriel G Thessing Jeffrey J Shaloski Michael M Frost Brian J BJ Li Liya L Seeram Navindra P NP

Inorganic chemistry communications 20091101 11

A series of half-sandwich arene-ruthenium complexes of the type [(eta(6)-p-cymene) Ru(thiosemicarbazone)Cl](+) have been synthesized and their biological activity investigated. The first structurally characterized arene-ruthenium half-sandwich complex with a thiosemicarbazone ligand is reported. ...[more]

PMID: 20160909

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Half-sandwich ruthenium–arene complexes with thiosemicarbazones: synthesis and biological evaluation of [(η⁶-p-cymene)Ru(piperonal thiosemicarbazones)Cl]Cl complexes.

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Assignment of Pre-edge Features in the Ru K-edge X-ray Absorption Spectra of Organometallic Ruthenium Complexes.

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Ruthenium complexes of sterically-hindered pentaarylcyclopentadienyl ligands.

Project description:The synthesis of ruthenium complexes incorporating an overcrowded pentaarylcyclopentadienyl ligand has been investigated, and higher efficiency has been reached using chlorine-functionalised precursors when compared with their brominated counterparts. A new methodology for the preparation of chlorocyclopentadienes has been developed which is well adapted for highly sterically hindered compounds and works with either electron rich or poor systems.

| S-EPMC9033943 | biostudies-literature

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