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Empirical typology of bipolar I mood episodes.


ABSTRACT: Much remains unknown about the phenomenology of bipolar I disorder.To determine the type of bipolar I mood episodes that occur over time, and their relative frequency.A total of 219 individuals with Research Diagnostic Criteria bipolar I disorder were prospectively followed for up to 25 years (median 20 years). Psychopathology was assessed with the Longitudinal Interval Follow-up Evaluation.Overall, 1208 mood episodes were prospectively observed. The episodes were empirically classified as follows: major depression, 30.9% (n = 373); minor depression, 13.0% (n = 157); mania, 20.4% (n = 246); hypomania, 10.4% (n = 126); cycling, 17.3% (n = 210); cycling plus mixed state, 7.8% (n = 94); and mixed, 0.2% (n = 2).Cycling episodes constituted 25% of all episodes. Work groups revising ICD-10 and DSM-IV should add a category for bipolar I cycling episode.

SUBMITTER: Solomon DA 

PROVIDER: S-EPMC2801829 | biostudies-other | 2009 Dec

REPOSITORIES: biostudies-other

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Empirical typology of bipolar I mood episodes.

Solomon David A DA   Leon Andrew C AC   Endicott Jean J   Coryell William H WH   Li Chunshan C   Fiedorowicz Jess G JG   Keller Martin B MB  

The British journal of psychiatry : the journal of mental science 20091201 6


<h4>Background</h4>Much remains unknown about the phenomenology of bipolar I disorder.<h4>Aims</h4>To determine the type of bipolar I mood episodes that occur over time, and their relative frequency.<h4>Method</h4>A total of 219 individuals with Research Diagnostic Criteria bipolar I disorder were prospectively followed for up to 25 years (median 20 years). Psychopathology was assessed with the Longitudinal Interval Follow-up Evaluation.<h4>Results</h4>Overall, 1208 mood episodes were prospectiv  ...[more]

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