Ontology highlight
ABSTRACT:
SUBMITTER: Norenberg A
PROVIDER: S-EPMC2818894 | biostudies-other | 2010 Jan
REPOSITORIES: biostudies-other
Nörenberg Anja A Hu Hua H Vida Imre I Bartos Marlene M Jonas Peter P
Proceedings of the National Academy of Sciences of the United States of America 20091222 2
Fast-spiking, parvalbumin-expressing basket cells (BCs) play a key role in feedforward and feedback inhibition in the hippocampus. However, the dendritic mechanisms underlying rapid interneuron recruitment have remained unclear. To quantitatively address this question, we developed detailed passive cable models of BCs in the dentate gyrus based on dual somatic or somatodendritic recordings and complete morphologic reconstructions. Both specific membrane capacitance and axial resistivity were com ...[more]