Ontology highlight
ABSTRACT:
SUBMITTER: Bruneau EG
PROVIDER: S-EPMC2822640 | biostudies-other | 2010 Jan
REPOSITORIES: biostudies-other
Bruneau Emile G EG Akaaboune Mohammed M
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100101 2
The efficacy of synaptic transmission depends on the maintenance of a high density of neurotransmitter receptors and their associated scaffold proteins in the postsynaptic membrane. While the dynamics of receptors has been extensively studied, the dynamics of the intracellular scaffold proteins that make up the postsynaptic density are largely unknown in vivo. Here, we focused on the dynamics of rapsyn, a protein required for the clustering and maintenance of acetylcholine receptor (AChR) densit ...[more]