Hematopoiesis and its disorders: a systems biology approach.
Ontology highlight
ABSTRACT:
SUBMITTER: Whichard ZL
PROVIDER: S-EPMC2845894 | biostudies-other | 2010 Mar
REPOSITORIES: biostudies-other
Publications
Hematopoiesis and its disorders: a systems biology approach.
Whichard Zakary L ZL Sarkar Casim A CA Kimmel Marek M Corey Seth J SJ
Blood 20100126 12
Scientists have traditionally studied complex biologic systems by reducing them to simple building blocks. Genome sequencing, high-throughput screening, and proteomics have, however, generated large datasets, revealing a high level of complexity in components and interactions. Systems biology embraces this complexity with a combination of mathematical, engineering, and computational tools for constructing and validating models of biologic phenomena. The validity of mathematical modeling in hemat ...[more]
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