Ontology highlight
ABSTRACT:
SUBMITTER: Bice P
PROVIDER: S-EPMC2867232 | biostudies-other | 2009 Mar
REPOSITORIES: biostudies-other
Bice Paula P Valdar William W Zhang Lili L Liu Lixiang L Lai Dongbing D Grahame Nicholas N Flint Jonathan J Li Ting-Kai TK Lumeng Lawrence L Foroud Tatiana T
Alcoholism, clinical and experimental research 20081219 3
<h4>Background</h4>The high and low alcohol preferring (HAP1 and LAP1) mouse lines were selectively bred for differences in alcohol intake. The HAP1 and LAP1 mice are essentially noninbred lines that originated from the outbred colony of HS/Ibg mice, a heterogeneous stock developed from intercrossing 8 inbred strains of mice.<h4>Methods</h4>A total of 867 informative SNPs were genotyped in 989 HAP1 x LAP1 F2, 68 F1s, 14 parents (6 LAP1, 8 HAP1), as well as the 8 inbred strains of mice crossed to ...[more]