Ontology highlight
ABSTRACT:
SUBMITTER: Christman MF
PROVIDER: S-EPMC287162 | biostudies-other | 1989 May
REPOSITORIES: biostudies-other
Christman M F MF Storz G G Ames B N BN
Proceedings of the National Academy of Sciences of the United States of America 19890501 10
The oxyR gene is required for the induction of a regulon of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium. The E. coli oxyR gene has been cloned and sequenced, revealing an open reading frame (305 amino acids) that encodes a 34.4-kDa protein, which is produced in maxicells carrying the oxyR clone. The OxyR protein shows homology to a family of positive regulatory proteins including LysR in E. coli and NodD in Rhizobium. Like them, oxyR appears to be negatively ...[more]