Ontology highlight
ABSTRACT:
SUBMITTER: Nucifora G
PROVIDER: S-EPMC287174 | biostudies-other | 1989 May
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19890501 10
Cadmium resistance specified by the cadA determinant of Staphylococcus aureus plasmid pI258 results from the functioning of a cadmium-efflux system. In the nucleotide sequence of the DNA fragment containing the cadA determinant, two open reading frames were identified. The larger one, corresponding to a predicted polypeptide of 727 amino acid residues, is necessary and sufficient for expression of cadmium resistance. Comparison of the CadA amino acid sequence with known protein sequences suggest ...[more]