Ontology highlight
ABSTRACT:
SUBMITTER: Melgert BN
PROVIDER: S-EPMC2874445 | biostudies-other | 2010 May
REPOSITORIES: biostudies-other
Melgert Barbro N BN Oriss Timothy B TB Qi Zengbiao Z Dixon-McCarthy Barbara B Geerlings Marie M Hylkema Machteld N MN Ray Anuradha A
American journal of respiratory cell and molecular biology 20090702 5
Females are more susceptible to development of asthma than are males. In a mouse model of ovalbumin-induced airway inflammation, with aggravated disease in females compared with males, we studied interactions between immune and resident lung cells during asthma development to elucidate which processes are affected by sex. We studied numbers of regulatory T cells (Tregs), effector T cells, myeloid dendritic cells (mDCs), and alternatively activated macrophages (AAMPhi), and their functional capab ...[more]