Ontology highlight
ABSTRACT:
SUBMITTER: Walmsley SJ
PROVIDER: S-EPMC2886813 | biostudies-other | 2010 Jun
REPOSITORIES: biostudies-other
Walmsley Scott J SJ Broeckling Corey C Hess Ann A Prenni Jessica J Curthoys Norman P NP
American journal of physiology. Renal physiology 20100310 6
The renal proximal convoluted tubule is the primary site of water, electrolyte and nutrient reabsorption and of active secretion of selected molecules. Proteins in the apical brush-border membrane facilitate these functions and initiate some of the cellular responses to altered renal physiology. The current study uses two-dimensional liquid chromatography/mass spectrometry to compare brush border membrane vesicles isolated from rat renal cortex (BBMV(CTX)) and from purified proximal convoluted t ...[more]