Ontology highlight
ABSTRACT:
SUBMITTER: Moustakas A
PROVIDER: S-EPMC2895775 | biostudies-other | 2010 Jun
REPOSITORIES: biostudies-other
OncoTargets and therapy 20100624
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults and carries the poorest prognosis. Despite recent progress in molecular biology, neuro-imaging and neuro-surgical care, the management of patients with GBM continues to harbor significant challenges. Survival after diagnosis is poor even with the most aggressive approach using multimodality therapy. Although the etiology of malignant gliomas is not known, the dependency of tumor growth on angiogenesis has id ...[more]