GSA-SNP: a general approach for gene set analysis of polymorphisms.
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ABSTRACT:
SUBMITTER: Nam D
PROVIDER: S-EPMC2896081 | biostudies-other | 2010 Jul
REPOSITORIES: biostudies-other
Publications
GSA-SNP: a general approach for gene set analysis of polymorphisms.
Nam Dougu D Kim Jin J Kim Seon-Young SY Kim Sangsoo S
Nucleic acids research 20100525 Web Server issue
Genome-wide association (GWA) study aims to identify the genetic factors associated with the traits of interest. However, the power of GWA analysis has been seriously limited by the enormous number of markers tested. Recently, the gene set analysis (GSA) methods were introduced to GWA studies to address the association of gene sets that share common biological functions. GSA considerably increased the power of association analysis and successfully identified coordinated association patterns of g ...[more]
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