Personalized therapies in the cancer "omics" era.
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ABSTRACT:
SUBMITTER: Ocana A
PROVIDER: S-EPMC2920264 | biostudies-other | 2010 Jul
REPOSITORIES: biostudies-other
Publications
Personalized therapies in the cancer "omics" era.
Ocaña Alberto A Pandiella Atanasio A
Molecular cancer 20100729
A molecular hallmark of cancer is the presence of genetic alterations in the tumoral DNA. Understanding how these alterations translate into the malignant phenotype is critical for the adequate treatment of oncologic diseases. Several cancer genome sequencing reports have uncovered the number and identity of proteins and pathways frequently altered in cancer. In this article we discuss how integration of these genomic data with other biological and proteomic studies may help in designing antican ...[more]
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