Ontology highlight
ABSTRACT:
SUBMITTER: Johansson F
PROVIDER: S-EPMC2920274 | biostudies-other | 2010
REPOSITORIES: biostudies-other
BMC bioinformatics 20100721
<h4>Background</h4>Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A variety of scores are available today but it is not clear how different scores relate to each other.<h4>Results</h4>We applied 25 conservation and variation scores to alignments from the Catalytic Site Atlas (CSA). We calculated distances among scores based on correlation coefficients, and constructed a dendrogra ...[more]