Ontology highlight
ABSTRACT:
SUBMITTER: Wittig M
PROVIDER: S-EPMC2922892 | biostudies-other | 2010 Sep
REPOSITORIES: biostudies-other
Wittig Michael M Helbig Ingo I Schreiber Stefan S Franke Andre A
Bioinformatics (Oxford, England) 20100706 17
<h4>Motivation</h4>Copy number variation (CNV), a major contributor to human genetic variation, comprises >/= 1 kb genomic deletions and insertions. Yet, the identification of CNVs from microarray data is still hampered by high false negative and positive prediction rates due to the noisy nature of the raw data. Here, we present CNVineta, an R package for rapid data mining and visualization of CNVs in large case-control datasets genotyped with single nucleotide polymorphism oligonucleotide array ...[more]