Ontology highlight
ABSTRACT:
SUBMITTER: Carayannopoulos LN
PROVIDER: S-EPMC2924803 | biostudies-other | 2010 Sep
REPOSITORIES: biostudies-other
Carayannopoulos Leonidas N LN Barks Jennifer L JL Yokoyama Wayne M WM Riley Joan K JK
Biology of reproduction 20100519 3
Murine models suggest that natural killer (NK) cells are important for normal implantation site development, in part, through the production of interferon gamma (IFNG). As KLRK1 (NKG2D) is expressed on human and murine uterine NK (uNK) cells, we examined the role of KLRK1 in the interaction between murine trophoblasts and NK cells. Flow cytometric analysis revealed that both murine trophoblast stem (TS) cells and differentiated trophoblast giant cells expressed the KLRK1 ligand retinoic acid ear ...[more]